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Hepatotoxin and Liver Damage – The Side Effects of CBD

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CBD Side Effects Liver Damage

In physics, the formula of Momentum is Mass multiplied by Velocity. If that’s the case, then the CBD Bandwagon is gaining momentum, day by day.  The rate at which people and nations are accepting its use and production propagates its velocity. The increasing popularity of the substance is leading more and more people and organizations to get on the CBD Bandwagon, increasing its support and mass. Combined, its slowly turning into an unstoppable force.

But what happens when that unstoppable force meets an immovable object? Nerdy physics and sagacious philosophies aside, its side-effects might just be the immovable object that it collides into. According to the Molecules Journal, Volume 24, Issue 9, CBD is not as harmless as its supporters make it out to be.

The Role of CBD in Medicine

But why do people use CBD in the first place? For starters, it’s the substance found in Cannabis that is non-addictive (THC is the addictive part). So, naturally, the belief that goes with that, makes it a lot less harmful than THC. Given its pain relieving and sleep-inducing properties, it provides the same effects with a lot fewer side-effects than its alternatives (like opium).

When we say “a lot less harmful” we mean “a lot less harmful” and not “harmless”, as most of its supporters are believing it to be. Sure, it has its own benefits not only with its restorative properties but also in its effectiveness in suppressing epileptic symptoms, as evidenced by the studies conducted by Devinsky and Sanjay Gupta. But that does not warrant a full green light for this product’s side-effects.

Cannabidiol’s Side Effects on the Liver

According to the study conducted for the Journal, the effects on the hepatotoxicity on 8-week-old mice have been observed. All the specimens were males and different groups have been tested with different dosage of CBD. These dosages were calculated and administered according to the mice’s bodies, meaning, the dosage administered for human subjects were scaled down to match the requirements of a mouse’s body.

The results showed a stunning 75% of the test subjects with a dosage above 615 mg/KG, showing signs of damaged liver, including increased bilirubin, LBW Ratios, AST and ALTs in just one day. The CBD definitely displayed some hepatotoxic behavior, but the Journal concludes it to be of a cholestatic nature, with a hint of “maybe”. While there have been a “maybe” on its nature, there was no doubt about its hepatotoxicity.

The Proper Use of CBD

With all the research going on, and the benefits of CBD being so clear, it’s hard to just stop right here and move on without using it. Now that the benefits of CBD have been widely accepted by the medical community, it’s time to look into its proper use with calculated doses. Because, to be honest, no modern medication comes without its own sets of side-effects anyway.

But if the studies were any indication of how CBD is going to react with human bodies, then we should remain well under the daily limit of 20 mg/KG dosage. In all honesty, even if we maintained that limit, we’d still be well below the 615 mg/KG dosage that resulted in the liver damage of the mouse subjects. That obviously doesn’t mean that 20 mg/KG is safe either since 615 mg/KG caused the damage in a day and lower doses might cause the same damage through long-term use. But if CBD is taken with proper care and in the right amounts, you could reap its benefits without its negative effects.

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Millennials are Preferring CBD Oil Treatments

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Milennials Are Preferring CBD Oil

The CBD Bandwagon has rolled too far to be pushed back into oblivion: or that’s what the recent studies believe. According to the study conducted by the NHS, about 50% of the millennials prefer to use CBD oil over prescription medicine any day. But what does that truly mean for the CBD Market? And why is it so important in the modern day world?

The Study

The National Health Services of England (NHS for short), has been funding different research behind providing better medical services to the patients. Recently, they had commissioned a study on 2000 adult subjects in the United Kingdom, in order to find the number of health-conscious millennials who are preferring to turn towards Cannabidiol oil as medication.

According to the studies, around 30% of the Britons are careful about going to psychiatrists for their mental ailments in the fear of being prescribed medicine that might be overkill for their symptoms; leaving them with severe side-effects and medicine dependencies. 38% of them are leaning towards CBD Oil for treating their symptoms, while 24% of the subjects prefer other holistic methods of treatment. Interestingly, if we separated these subjects with respect to their age, we can see that almost 50% of the millennials in the UK prefer to use CBD as a treatment for their mental ailments.

CBD Benefits

We have already spoken about the benefits of CBD countless times on our website. But for the newer readers among you, a slight recap might be in order for you to understand why so many people are leaning towards it nowadays. First of all, CBD is the component of Cannabis that isn’t addictive. This is a big deal as it helps its user to ensure that he or she will not become dependent on this medicine once he or she starts using it.

Second, it has many reported benefits in the beauty industry, the medical industry as well as in the world of psychiatry. In terms of beauty, its topical use can provide smoother skin, reduce dryness, reduce acne breakouts and ease skin irritation. As for its medicinal properties, it is a great pain reliever and can be considered as an alternative to a lot of other addictive painkillers such as opium.

It works great as a stress-reliever, anxiety reducer and sleeps inducer. But its most prominent use would most likely be the properties that make it suitable to be used as a medication for controlling epileptic seizures. With little to no side-effects, the benefits of CBD is huge.

How it affects the Market

After seeing such a rise in its popularity among different age groups, it’s no surprise that CBD can have a great impact on the market. According to different estimates, the CBD might hold a 17 Billion USD market in the world for beauty treatments and over 20 Billion in combined markets, by the year 2024. With such prospects dangling in the horizon, it’ll hardly come as a surprise if this research incites the British Government to relax some of their laws concerning this substance.

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CBD Helps Pets Calm Down During Firework Stress

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CBD Pets Stress

Fourth of July noise

We all love a loud celebration. But our pets? Not so much. With the Fourth Of July upon us, many pet owners are turning to products that can help keep their pets calm during the explosive celebration. Many of the newer products in this category contain the active ingredient cannabidiol or CBD.

Stormy may be an ironic name for a dog because her name definitely doesn’t suit her dislike for loud noises. According to her owner, Hanbee Choi, Stormy is not a fan of loud noises like the vacuum, and of course, fireworks and firecrackers aren’t an exception. She also said that Stormy would hide under places whenever she’d hear the loud noises.

CBD helps pets calm down

Choi dropped by Chuck and Don’s pet store to look for products that will help with her pet’s stress and anxiety. She looked for products that contain the specific ingredient of cannabidiol or CBD. It’s a product derived from hemp that’s a powerful supplement. This particular compound is famous for its many health benefits without the intense side effects.

Elizabeth Hayden, the pet supplies store’s assistant manager says that CBD can cure diseases like a seizure, and also help alleviate pain, anxiety, stress, inflammation, etc. More customers are going for any CBD products in the form of a chewable tablet or gummies or concentrated oils. These CBD products are not like prescription drugs from veterinarians wherein you have to slowly wean off pets from it. They can be given to pets as needed, without the need to gradually decrease the dose as with the usual drugs given by vets.

Choi shares that CBD helps keep her dogs calm during car rides. She said that with CBD oil, her dog wouldn’t throw up or have any stomach issues during car rides. It kept the dog calm, allowing him to law down and go to sleep.

Keeping your pets calm during the noise

Staff recommends still placing pets in a quiet place on the Fourth of July or any day where you would anticipate fireworks. CBD-containing products should only be used in conjunction with that. You can place your pets away from windows or open spaces and play some music to drown out the noise.

The staff of the pet store supplies suggests that pet owners consult with their vets first before trying out any CBD products especially if they are also taking other drugs that may interfere with it. However, pet owners shouldn’t worry much about the side effects when using CBD on their pets. Many studies have proven the health benefits of CBD on pets as well as its safety even when taken at high doses or just occasional use.

Ultimately, CBD can be a life-saving supplement for your pets. It has significant calming effects on your pets that you will surely appreciate during times of stress like firework season

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Senators promote cannabis and CBD research

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CBD Senators

Cannabis is promoted at the Congress

Cannabidiol, also known as CBD, is one of the key components of marijuana. It’s becoming more and more popular nowadays for its most sought after health benefits. It’s currently garnering more attention than THC because of its relatively milder and less intense side effects. CBD is a non-psychoactive component of marijuana, thus, it doesn’t affect mentation and behavior.

Senators Dianne Feinstein, Chuck Grassley, and Brian Schatz are responsible for the new Cannabidiol and Marijuana Research Expansion Act. They moved that marijuana, as well as CBD research, be a priority to further expand scientific research of medical cannabis and boost the support of its legalization. The bill would change marijuana’s definition in the Controlled Substance Act. This would entail that hemp-derived synthetic equivalent of CBD containing no more than 0.3% tetrahydrocannabinol or THC would no longer be considered as marijuana.

 

The Federal Bill and its Main Provisions

In the said act, the U.S. Food and Drug Administration would play a part in making sure medications that contain or are derived from marijuana are regulated and safe. Because of this, extensive research regarding the medical benefits of marijuana and its derivatives should be made. Moreover, licensed doctors can also discuss CBD or marijuana’s medical advantages and disadvantages as a treatment option for their patients.

The senators have stated parents’ testimonies regarding CBD and marijuana in the treatment of various childhood illnesses such as severe epilepsy, which is very difficult to treat through the means of traditional western medicine. Thus, they have ruled in the potential value of CBD in treating these resistant diseases.

The bill would call for a faster and more streamlined process in reviewing medical marijuana research. This would also mean a more efficient development of medicine derived from CBD and marijuana, through the approval of the FDA. Lastly, the bill requires the Department of Health and Human Services [3] to let the Congress in the know about the potential harmful or beneficial effects of marijuana and marijuana-containing drugs on the human body, brain, and mental faculties.

CBD in the modern setting

The use of CBD in day-to-day lives is increasing among more people every day. One of the most common ways people use CBD is through cannabidiol or CBD oil. Among the most frequent reasons for CBD, oil use is pain, sleeplessness, and anxiety. For most people, it even has a positive impact on their focus and mind clarity during the day. It’s been an ideal companion for most people who are under constant stress. As previously mentioned, parents are also trying to use this as a cure for difficult to treat childhood illnesses such as epilepsy. Because of this, lawmakers have made it a priority to expand scientific and evidence-based knowledge regarding marijuana or CBD’s efficacy and safety in treating a variety of medical conditions that are otherwise refractory to modern medicine.

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