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State sharpens Franklin Labs-LECOM medical cannabis research center plan

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State sharpens Franklin Labs-LECOM medical cannabis research center plan

A Reading-based firm that intends to associate with the Lake Erie College of Osteopathic Medicine on medical marijuana study will reapply for a license from the Pennsylvania Department of Public Health following its first application was refused.

The Pennsylvania Department of Health refused the software of eight candidates who hunted growing/processing and dispensary licenses within their nation’s medical marijuana research plan. One of the candidates was Franklin Labs, which has partnered with all the Erie medical institution to conduct the study.

“They’re frustrated,” LECOM spokesman Pierre Bellicini stated in a brief statement after speaking with Franklin Labs officials. “Franklin Labs is working on another step and thLey intend to use .”

Also Read: Reduce taxes and regulations on Marijuana, says some at forums

The health division rejected Franklin Labs’ application as it failed to incorporate a legal contractual relationship with an academic research center, according to a letter that the health department delivered Tuesday to Franklin Labs CEO Berchard Suber.

Franklin Labs’ contract with LECOM was considered invalid because it had been signed prior to the medical school was licensed as an academic clinical research center in the nation’s medical marijuana program. LECOM was certified in May.

Two other candidates were rejected for the identical reason. Others have been rejected for failing to incorporate a dispensary program and required fees, for failing to meet minimal program scores or for not following instructions, philly.com documented.

“Our purpose is to make sure that our study program works at the greatest standards,” Pennsylvania Health Secretary Rachel Levine, M.D., stated in a news release. “We’re disappointed that awards weren’t made, but have to uphold the criteria set out in regulations.”

The study plan is part of Pennsylvania’s Medical Marijuana Law and has been revised, following a Commonwealth Court judge issued a preliminary injunction in May, to need medical department endorsement of the firms with whom every college spouses, philly.com registered.

Also Read: Recreational marijuana is now legal in Michigan from Today

State officials said the application could place Pennsylvania one of the leaders in medical marijuana study but present licensees have stated they stress it is just another way providers can secure licenses without moving through the rigorous application procedure they did.

Every firm that receives a license could grow bud and start as many as six dispensaries in the nation.

“We are all responsible for the medical investigation. But this does not look like medical investigation as far as a mechanism for organizations to bypass the software process we failed,” GTI CEO Pete Kadens stated earlier this season.

GTI owns and works Rise Erie, Erie’s sole legal medical marijuana dispensary.

A group of farmers and dispensary operators at Pennsylvania filed a suit Nov. 27 from the health area. The team, called Medical Marijuana Advocates for Research, stated they consider the law’s developments concerning the research plan still do not create the vetting procedure transparent enough.

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Light Cannabis Legalized – Study reveals a decrease in the sales of pharmaceutical drugs

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Decrease in Sales of Drugs

Light cannabis or low THC hemp derived flowers used to be sold freely at shops all across the country before Italy’s interior minister declared a war against the substance using a legal loophole.

People are still skeptic whether or not will the substance be allowed to sold again and used without any stringent restrictions from June onwards. The nation’s Supreme Court of Cassation is expected to look into the matter and discuss the legality of hemp-derived cannabinoid later this month.

According to a new study, the sales of medicinal drugs declined dramatically after light cannabis was introduced in the market. The pharmaceutical industry as a whole saw a massive drop since the new light cannabis came into action around 10 months back.

Researchers in York University, UK wrote that after the introduction of the policy which legalized light cannabis in a given province, they noticed a reduction in the number of dispensed boxes of anxiolytics by almost 11.5%, decrease in dispensed sedatives by 10% and a gradual decrease in anti-psychotics by 4.8%.

In 2016, a new law was enacted in Italy regulating hemp production which unintentionally set off a “green gold rush”: Cannabis flower with 0.2% or fewer traces of THC became legal to sell and purchase as a collector’s item. People can buy jars filled with hemp flower but can’t consume it.

Contrary to the federal law which passed the Farm Bill 2018 in the United States that removed hemp derived cannabinoid from its list of Controlled Substance Act with a set of regulatory reforms, Italy removed certain restrictions which resulted in the prompt actions taken by companies and retailers that allowed them to sell hemp flower as a “technical product.”

A study published in the Health Econometrics and Data Group Working Paper series is a new study which sheds light on the newly legalized low THC levels cannabis.

The study’s authors found that the unintended liberalization of light cannabis opened up new pathways for cannabis research and led to some jaw-dropping research revelations that could prove to be a turning point for the medicinal industry. It also created a great entry point to study the behavioral pattern of the users taking hemp flowers for their medicinal use and how it could reduce the consumption of medicinal drugs.

The light cannabis overpowered other pharmaceutical drugs including opioids, anxiolytics, anti-migraine, anti-depressives, antipsychotics, sedatives and anti-epileptics.

For their research, they gathered monthly data on pharmaceutical drug sales for all 106 Italian provinces from January 2016 to February 2018. On a monthly average, they found that the Italian health authority provides reimbursements for 28 packets of sedatives and 72 boxes of anxiolytics per province.

They also recorded the reimbursement of 12,610 packets for opioids, 27,198 packets for anti-depressants, 4,802 packets for antipsychotics, 27,198 for anti-depressants, 2,504 boxes for anti-migraines and 18,460 packets for anti-epileptics.

With the ease of accessibility to light cannabis at retail stores, the average number of dispensed pharmaceuticals decreased by approximately 1.6%. The most common ailment targeted by these drugs were mental disorders or stress issues that patients were suffering from.

It is known that hemp derived cannabinoid with low levels of THC or 0% THC can help reduce pain, anxiety, inflammation, stress, depression and also cure severe ailments such as Cancer, epilepsy, and seizures. Though there is no internationally recognized study which supports these claims, patients have reported significant benefits after using CBD just for a few days.

The study concluded that even a mild form of liberalization may generate a significant effect on the pharmaceuticals market. Researchers encourage lawmakers and stakeholders to form regulatory policies to ensure safe and healthy consumption of the substance without putting any lives at risk or harm.

Meanwhile, in the U.S., the Food and Drug Administration has announced a public hearing on May 31, where it will discuss the regulatory model and the impact of CBD with stakeholders. They have kept the forum for discussion open until the next month after which serious evaluation will be done and a final decision can be expected. However, as per Scott Gottlieb, the Commissioner of the FDA said it could take several years for the regulatory model to be announced.

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CBD Oil Can Help you Sleep [According to the latest Study]

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I’m sure many of you have, at one point in your journey to wellness, wondered if CBD oil can help you sleep.

This is actually a sensible question because it is no secret that one of the benefits of CBD is the relief from insomnia and other sleep-related difficulties.

Therefore, it’s only natural to think that if CBD oil can help us sleep better, doesn’t it also mean that we will tend to feel sleepy whenever we take it?

Well, to better get to the bottom of things, let us first take a look at how CBD works in our bodies.

The Relationship Between CBD and the Endocannabinoid System (ECS)

The ECS is a network of receptors that are found within our bodies. When we take in CBD, it interacts with these receptors to provide relief from a number of medical symptoms.

ECS affects our appetite, pain modulation, memory, appetite, and mood. In essence, it helps regulate many of our bodily functions and physiological processes.

Homeostasis is achieved when CBD successfully works together with our ECS. When our bodies function efficiently, this helps relieve stress.

Anxiety and insomnia are two of the most common conditions that people want to treat with CBD.

Now, there are already a number of studies and research that offer proof with regards to how CBD can successfully relieve symptoms of insomnia.

However, the way CBD works may not be what you had in mind.

Yes, CBD oil can make you sleepy, but there are certain conditions make this happen.

Unlike other medications like sleeping pills and THC, CBD gets to the root of the problem. 

Stress, Anxiety, Depression, and Their Effect on Sleep

Like other diseases, insomnia and other sleep problems stem from other issues. In this case, it may be from being too stressed out, anxious, or tense.

You have no doubt already experienced how it is to lie down in bed with several troubling thoughts preventing you from falling asleep right away. This is a lot different from moments when you feel relaxed by the time you have to sleep.

During these occasions, you most probably fall asleep in no time at all, and you feel well-rested by the time you wake up in the morning. Accordingly, a longer and better quality of sleep results from a calm state of mind.

CBD Can Relieve Stress and Other Disruptors of Healthy Sleep

Many factors in today’s fast-paced lifestyle contribute to an increase in people’s stress levels. This is why many have turned to CBD to deal with this situation.

If not addressed quickly enough, stress can also lead to anxiety and depression, further aggravating sleep problems.

I don’t have to tell you that CBD oil does a fantastic job with helping people feel calm and relaxed. There is already a plethora of information online that attests to this.

Moreover, even those who find it difficult to get a good night’s rest because of chronic pain and other health conditions will also benefit from CBD oil.

Simply put, if you eliminate the source of sleep difficulty, you are well on your way of achieving the sleep quality that you long for.

Why Do Some People Feel Drowsy When Taking CBD Oil?

As I’ve said, CBD oil can make you sleepy even if you are not taking it for sleep difficulties. However, there are particular factors that make this so.

Aside from the fact that everybody is different, CBD dosage and some cannabis compounds also influence the effect of CBD oil on a person.

  • THC, the psychoactive component of cannabis, is said to have an effect on sleep. A review has shown that THC can make a person fall asleep.
  • Some terpenes found in the cannabis flower can enhance the sedative effect of the cannabis plant. Terpenes are basically chemicals in the cannabis flower that give out a scent and are also in the essential oils of plants.
  • Stale cannabis can make you feel sleepy and tired because cannabinol (CBN) in old leaves and buds are greater in quantity.
  • The strain of cannabis plant can also affect its sedative effect. Between the indica and sativa strain, indica is reported to have a more soporific influence. This is why indica strains are more suitable for nighttime doses.
  • Lastly, dosage plays a significant part in whether or not a CBD oil can make you sleepy.

Interestingly, when CBD is taken in low doses, we typically feel more alert and stimulated. We also feel more relaxed and calm without feeling sleepy.

The opposite happens when we take CBD in higher doses. We will usually feel drowsier, and we get to sleep well through the night.

As a precaution, make it a habit to check out the lab test results that your CBD oil brand provides online. Look at the cannabinoid and terpene profile and the cannabis strain of your product.  

Additionally, experiment with various doses and experience for yourself which one will best provide you with the drowsiness you want.

Remember, too, that depending on your method of taking in CBD, the time it takes for the effects to be felt can range from mere minutes to a couple of hours.

In the End, It All Comes Down to How You Take Your CBD Oil

In all honesty, CBD is remarkable and can help improve the lives of people who use it. Just read the testimonies of those who chose to give it a try, and later got to experience its healing effects. As to whether or not it can make you sleepy, it can indeed can, but only if you want it to.

CBD oil can help us manage our anxiety, pain, and stress levels, leading to a more restful sleep at night. When taken daily while following the appropriate dosage, it can help us relax without making us feel drowsy.

I encourage you to do your research and try out for yourself.

 

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Does CBD Oil Have Side Effects? Studies Say Yes, It Does

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Discussion forums about Cannabidiol have increased fairly recently since the advent of the plant-based cure.

Informative websites regarding the herbal medicine have also risen, discussing the nature and the healing benefits of CBD oil.

There may be users who trust in the healing properties of plant-based medicine. Alternatively, there are those who question its validity as a curing agent.

But is CBD oil, indeed, worth the people’s trust?

Is it really impeccable in curing nearly a hundred health concerns?

What are its side effects?

Nature and Current Scenarios Involving Cannabidiol Oil

The organic marijuana plant has more than 113 cannabinoids. Although the delta-9-tetrahydrocannabinol (THC) is the major active component of cannabis, cannabidiol (CBD) comprises approximately 40 percent of cannabis extracts. Also depends on the type of plants.

This component CBD oil has been the subject of myriads of research undertakings for its plenty of uses.

In addition, CBD has been reported to prevent users from getting “high,” blocking this feature of the THC.

The Food and Drug Administration (FDA) does not consider products that consist of CBD as dietary supplements. The reason behind this is because it is a fairly new drug, which is still being studied.

However, despite this declaration of the FDA, dietary supplements that claim to have CBD as a component teem in today’s markets.

Consumers are advised to be wary because CBD in these products is not accurately indicated in the packaging.

The FDA has also warned that, although positive feedbacks and testimonials about the beneficial natures of CBD oil seem ubiquitous nowadays, consumers should personally be vigilant.

Wellness Advantages of Taking Cannabidiol

It has been reported to be capable of treating mild to serious ailments. Among these health concerns are anxiety, bipolar disorder, dystonia, and seizures.

In addition, patients having Parkinson’s disease, multiple sclerosis, and schizophrenia are reported to have found relief using the oil.

Chain smokers who are finding it difficult to part ways with their unhealthy habits are also saved by CBD oil.

With these wholesome benefits, does taking the oil involves inconveniences as well?

Side Effects of Taking CBD Oil

CBD oil side effects

There have been few reported detrimental effects associated with taking CBD oil. Users of the oil should not be concerned though since those affected are a few in number.

In addition, these potential side effects are manageable.

1) Lethargy and Sleepiness

CBD oil’s effects can vary from one user to another. For some, it is mind-stimulating. They feel awake after taking the oil. In addition, they feel energized and in a better mood.

However, for other users, the oil can make them feel the opposite. When consuming high doses, they would experience drowsiness.

As a safety precaution, it is advisable not to drive. In addition, a drowsy CBD oil user should keep away from using heavy machinery or driving.

2) Increase in Quivering Motion

This likely side effect is linked to patients with Parkinson’s disease.

3) Weakness and Unsteadiness

Users may experience the temporary side effects of lightheadedness. This uneasy feeling is associated with the modest plummet in blood pressure.

To alleviate the feeling of fainting, taking a cup of coffee would help, regulating the body to its normal and proper state.

Furthermore, if coffee is not available, taking a cup of tea helps as well as drinking plenty of water.

These remedies will keep the body hydrated, and the caffeine component of the tea or the coffee will awaken the user’s senses.

4) A Slight Plunge in the Blood Pressure

Some researchers discovered that taking higher dosages of CBD oil can cause a user’s blood pressure to drop in small counts.

The uncomfortable feeling of lightheadedness may inconvenience the users who experience this side effect.

In this manner, users who have been diagnosed with low blood pressure or are under medication because of this health concern are advised to speak to their physicians prior to consuming CBD-based products.

5) Dehydrated mouth

The secretion of saliva in the mouth can be inhibited by the endocannabinoid system. This is possibly a consequence of CBD oil’s engagement into the processes of the system.

Thus, dry mouth is experienced by the oil’s users. This side effects can be managed by drinking hydrating fluids during the time of consuming the product and after doing so.

Hydration can also prevent the unwelcome loss of water in the body or getting dehydrated.

6) Modifications in Appetite

Based on studies by the National Cancer Institute, CBD oil can help stimulate a user’s appetite.

If he is troubled by some disease that decreases his desire to eat, taking the oil will help him regain his appetite, helping his body heal through a healthy diet.

7) Diarrhea

Some users of the oil may experience mild upset stomach, which includes diarrhea.

8) Interaction with Other Medications

It may interact with other drugs like the valproic acid, a conventional seizure medicine that is used to heal bipolar disorder and depression.

The oil is also allegedly interacting with blood thinners. Other mild side effects of CBD oil include feeling irritable, nausea, exhaustion, and trouble sleeping.

Medical professionals and scientific experts may consider it as harmless for most people to take. Serious side effects may happen rarely.

Apparently, the vast majority of users take the plant-based medicine without ever complaining about the adverse side effects at all.

Quite a few would report that they experienced a dehydrated mouth or are discomforted by diarrhea.

In fact, the World Health Organization has confirmed that CBD oil has no effects that indicate that users can abuse it or become dependent on it.

The international organization also affirmed that the oil is “generally well-tolerated with a good safety profile.”

Apparently, impurities present in inferior or substandard CBD oil products are the culprit for the detrimental side effects that have bedeviled the consumers.

Therefore, it is highly recommended to perform careful research about CBD oil products before purchasing.

Consulting with a physician and asking for advice is also an auspicious measure. In this manner, a user would only get the best and the safest CBD oil product and be safeguarded from any health inconveniences.

References:

https://cbdoilreview.org/cbd-cannabidiol/cbd-benefits/

https://www.healthline.com/nutrition/cbd-oil-benefits#section8

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602/

https://www.webmd.com/vitamins/ai/ingredientmono-1439/cannabidiol

http://www.who.int/medicines/access/controlled-substances/5.2_CBD.pdf

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